Knowledge Center

Chemistry and outsourcing knowledge for drug development teams

Guides on CAS identification, pharmaceutical intermediates, synthesis methodology and CRO/CDMO collaboration, written by our scientific team.

Pharmaceutical Intermediates

Quality Control of Pharmaceutical Intermediates

Identity, assay, impurity profile and residual solvents are the four pillars.

2025-05-30

Industrial Insights

Fluorinated Building Blocks in Drug Design

Fluorine substitution changes metabolic stability, acidity and binding.

2025-05-12

CRO / CDMO

Choosing a CRO or CDMO Partner

Evaluation criteria for outsourcing synthesis and manufacturing.

2025-04-25

Drug Development

Scale-Up From Gram to Kilogram

What changes when a laboratory route moves into a pilot plant.

2025-04-08

Chemical Synthesis

Boronic Acids in Suzuki Coupling

Why boronic acids remain the workhorse coupling partner in medicinal chemistry.

2025-03-19

CAS Number Guide

Understanding CAS Number Check Digits

How the last digit of a CAS Number validates the rest of the identifier.

2025-03-02

Chemical Synthesis

What Is Custom Chemical Synthesis?

Route design, multi-step synthesis and delivery of non-catalogue molecules to customer specification.

2025-02-18

Pharmaceutical Intermediates

What Are Pharmaceutical Intermediates?

Intermediates are the isolated compounds produced on the way from starting material to active pharmaceutical ingredient.

2025-02-04

CAS Number Guide

How to Search Chemicals by CAS Number

Exact-match CAS searching, synonym searching and molecular formula searching explained.

2025-01-22

CAS Number Guide

What Is a CAS Number?

A CAS Registry Number is the universal identifier for a chemical substance, independent of name or language.

2025-01-14

Looking for a Specific Compound?

Send us your CAS Number, chemical structure or project requirements and our scientific team will evaluate your request.

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